Phosphorylation of Myosin by Adenosine Triphosphate
نویسندگان
چکیده
منابع مشابه
Adenosine triphosphate inhibition in myosin adenosine triphosphate systems.
Factors affecting inhibition of myosin ATPase by ATP, such as concentration of the enzyme, of ATP, and of the divalent metals, calcium and magnesium, have been studied and the results are reported here. Experiments were carried out under conditions in which no known magnesium effects occurred, so that only the effect of calcium on the nucleoside triphosphatase activity of myosin A could be qual...
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Muscle contraction may be simulated in nitro by addition of Mg2+ and ATP to threads containing just two proteins, actin and myosin, in an aqueous medium. Shortening occurs by the interdigitation of the actin and myosin filaments, presumably driven by the cyclic attachment of cross-bridges, which are projections of the myosin filament containing the ATPase* site. The rationale for studying the m...
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For the simplest kinetic model the reverse rate constants (k(-1) and k(-2)) associated with ATP binding and cleavage on purified heavy meromyosin and heavy meromyosin subfragment 1 from rabbit skeletal muscle in the presence of 5mm-MgCl(2), 50mm-KCl and 20mm-Tris-HCl buffer at pH8.0 and 22 degrees C are: k(-1)<0.02s(-1) and k(-1)=16s(-1). Apparently, higher values of k(-1) and k(-2) are found w...
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Previous reports from this laboratory have demonstrated that the ATP-Pi32 1 exchange reaction (1) and the dinitrophenolstimulated ATPase activity (2) of mitochondrial subfragments (3-9) are reflections of intermediate enzymatic steps in the complex sequence of reactions (1, 3) in which phosphorylation of ADP is coupled to electron transport in the respiratory chain. This communication concerns ...
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phosphorylation or photophosphorylation is a multi-step, membrane-located process that provides the bulk of cellular energy in eukaryotes and many prokaryotes. Most of the ATP synthesis in these cells is catalyzed by the enzyme, F1Fo-ATP synthase, also called F1Fo-ATPase (F-ATPase), which in its simplest, bacterial, form is composed of eight subunits (α3:β3:γ:δ:ε:a:b2:c9–12). The archaeal A1Ao-...
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ژورنال
عنوان ژورنال: Nature
سال: 1948
ISSN: 0028-0836,1476-4687
DOI: 10.1038/162965a0